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Live examples

Live Examples of what types of visualizations and analyses you can perform using UCSC Xena

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Workshop cheatsheet/handout

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Xena_Workshop_handout.pdf
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Xena Workshop Handout

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FOXM1a, FOXM1b, FOXM1c transcript expression in tumor vs. normal samplesarrow-up-right

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Xena mutation views supports examination of both coding and non-coding mutations from whole genome analysis. We support viewing mutations from both gene- or coordinate- centric perspective. In the gene-centric view, you can dynamically toggle to show or hide introns from the view. This figure shows the frequent intron mutations in 321 samples from the ICGC lymphoma cohorts. These 'pile-ups' would be not be visible if viewing mutations only in the exome. These intron mutations overlap with known enhancers regions (Mathelier 2015).‌

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PDL1 and PD1 expression across 39 cancer types in TCGA and TARGETarrow-up-right
MGMT gene expression ~ promoter DNA methylation in GBMarrow-up-right
ERG-TMPRSS2 fusion in prostate cancerarrow-up-right
KM plot of breast cancer PAM50 subtypesarrow-up-right
Genetic separation of lower grade gliomas: one characterized by loss of chromosomes 1p & 19q, the other by TP53 & ATRX mutationsarrow-up-right
Copy number for EGFR, PTEN, chromosome 1, 7, 10, 19 in TCGA brain tumorsarrow-up-right
Mutation pile-ups in intron enhancers in ICGC lymphomaarrow-up-right
Stemness scores across TCGA cancer typesarrow-up-right
https://xenabrowser.net/heatmap/?bookmark=634da50313613e659e865c2bfb958ea1arrow-up-right
https://xenabrowser.net/?bookmark=16e1d1a37ab7d9820a6bf1399ce5135earrow-up-right
https://xenabrowser.net/?bookmark=048e461b1819bc84808edc16b34e974barrow-up-right
https://xenabrowser.net/heatmap/?bookmark=2e553fc5ca9858653e225fabce0c36abarrow-up-right
https://xenabrowser.net/heatmap/?bookmark=c03d52bed79d2b474ffcef679796a12darrow-up-right
https://xenabrowser.net/heatmap/?bookmark=d5de509a8ff0032298a0547c97638e3farrow-up-right
https://xenabrowser.net/heatmap/?bookmark=c6429007551de3bf0ea491c96814a1cfarrow-up-right
https://xenabrowser.net/heatmap/?bookmark=ba5edb23fe570ef22f5f518859ca0911arrow-up-right
https://xenabrowser.net/?bookmark=046e741291000b1b366c70ec5a3cd39farrow-up-right
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0648-7genomebiology.biomedcentral.comchevron-right